Research Approach:

Supramolecular Chemistry for Life-like Materials

Our research programmes are designed and orientated to exploit the full intrinsic potential of synthetic organic chemistry to build new supramolecular structures, functions and hierarchical systems. As inspired by nature’s structural beauty and sophisticated functional processes, our major goal is to design novel supramolecular functional systems, across length-scale, into stimuli-responsive functional soft materials with focus on following two major areas:

(I) Like-like Supramolecular Soft Actuators
The research program aims to develop highly dynamic, reversible, and biocompatible supramolecular soft actuators, which is complementary to existing polymeric soft actuators. Currently, macroscopic materials shape transformations, materials cargo transport, and dual-controlled supramolecular soft actuators have been developed. What are the existing challenges? How to recognize the potential applications? How to make the systems biocompatible?








Selected Publications:
F. K. C. Leung et al. Angew. Chem. Int. Ed. 2019, 58, 10985; DOI
F. K. C. Leung et al. J. Am. Chem. Soc. 2018, 140, 17724; DOI
F. K. C. Leung et al. Nat. Chem. 2018, 10, 132; DOI

(II) Controlled Supramolecular Transformations of Hierarchical Systems
The research program is designed to control reversibly transformations of supramolecular assembly and organizations at different hierarchical levels, in supramolecular soft materials and self-assembled two-dimensional structures on various substrate surfaces, e.g., nematic lyotropic liquid crystals, hydrogels, and responsive surfaces.

Selected Publications:
F. Xu et al. Chem. Commun. 2020, 56, 7415; DOI
S. Chen et al. J. Am. Chem. Soc. 2020, 142, 10163; DOI
F. K. C. Leung et al. J. Am. Chem. Soc. 2016, 138, 11727; DOI